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Short History of Diabetes Mellitus The name "diabetes" is a Greek word meaning "to siphon," which is quite reflective of how one’s life force is drained from oneself when afflicted with this disease. Approximately 1,424 years later in 1674, Dr. Thomas Willis, personal physician to the late English King Charles II, described the sweet taste of urine from diabetics "as if imbued with honey and sugar" - hence, the name "mellitus" is Latin for honey. This is how the modern day term "diabetes mellitus" came into being. InsulClearä for Type II Diabetes (Patent Pending)
Diabetes Type II, called "Insulin Resistant": Paradoxically, there is enough insulin, but it does not work efficiently to break down the sugar as fast as it should. Thus, one has a rise in blood sugar levels as in a Type I Diabetic. Because the body has become resistant to the action of insulin, Type II Diabetics are known as "insulin resistant." Blood sugar levels rise after a meal, and as the meal is digested, glucose is absorbed into the bloodstream, thereby causing the pancreas to produce enough insulin to return the blood sugar to a normal range. This is where it becomes a "sticky wicket," or a "round robin" scenario. Type II Diabetics’ cells have become resistant to insulin (they do not recognize the pancreas-produced hormone insulin) and are unable to move glucose from the bloodstream into the cells. To compensate for the increased levels of blood sugar in the bloodstream, the pancreas produces more insulin.1 Outside of each cell within one’s body, there are "insulin receptors." These insulin receptors are what regulates the amount of sugar that flows into one’s cells. When they are not working efficiently, one’s sugar level rises and the body counters this by producing more insulin. This additional insulin causes the insulin receptors to become even less effective, or lazy, thereby raising the blood sugar even more. This in turn causes the pancreas to produce more insulin, and the insulin receptors become ever more ineffective. This vicious cycle or "round robin" continues until one becomes insulin resistant, or a full-blown Type II Diabetic. Research has shown an overabundance of insulin in one’s body is very detrimental (toxic) to one’s health, according to Peter H. Forsham, M.D., of the Evergreen Hospital in Kirkland, Washington. He noted, "Excess glucose in diabetes can diminish the biological effectiveness of various proteins in one’s body." Citing an example, he went on to say, "When glucose binds to hemoglobin (the iron-containing pigment of the red blood cells), the oxygen-carrying capacity of hemoglobin is reduced." One’s body must get the sugar out of the bloodstream and into the cell where it can metabolize in the mitochondria into energy known as adenosine triphosphate (ATP). This is the reason why diabetics feel fatigued and lethargic all the time, due to a high blood glucose level. 2 Once sugar is able to pass through the cell wall, the mitochondria, the powerhouse of one’s body, it is able to break down the sugar along with the oxygen into ATP, the fuel that is needed to run one’s body. The unused portion of the oxygen that is not properly utilized becomes free radicals, which are highly unstable molecules filled with bursting energy. The repercussions from the damaging effect of these free radicals are believed to produce various diseases in one’s body, including cancer, diabetes, heart disease, Parkinson’s disease, cataracts, and arthritis. These damaging free radical molecules must be checked with antioxidants, or free radical scavengers (liken to carp fish) that gobble them up before they ravage one’s cellular structure.What is INSULIN? Insulin is a hormone that is needed to metabolize one’s body sugar and starches. If the insulin is unable to metabolize the sugar and starches efficiently, the blood sugar becomes unstable with excess amounts of sugar in the blood and urine, due to the "insulin receptors’" inability to perform as they were designed. Because insulin has not been able to metabolize the sugars in one’s body, the cells in one’s body are unable to utilize the sugars; thus, the buildup of excess sugar in one’s blood and urine. One is then faced with the prospect of Type II Diabetes, referred to as "insulin resistant." 3Where does INSULIN come from? The hormone insulin is produced from one of the body’s endocrine glands, the pancreas. It is a gland located below and behind the stomach and liver. 4 Special cells within this gland, called islets of langerhans, manufacture insulin.5 The pancreas is controlled by the endocrine pituitary gland, located exactly in the center of the brain, and what is called the master gland. This gland controls the release of most of the body’s hormones. The anterior pituitary lobe is one lobe of three that make up this gland. It is responsible for secretion of ten hormones within one’s body. Connected to the pituitary gland by tiny capillaries is the hypothalamus, which communicates with the rest of the body through a nervous system these various hormones, released by the pituitary gland. The hypothalamus gland is a jack-of-all-trades in one’s body. It controls various aspects of one’s body such as stimulation of muscle fibers, secretions of growth hormone, thyroid gland function, mammary glands, sleep center, emotions, appetite, heat production, and the thermoregulation of the body. This dual axis between these two glands regulates the activity of growth hormone (GH), sex glands, thyroid glands, and the adrenal glands, which in turn control one’s stress level and response.6 The hypothalamus is liken to the bridge of a large ship, the command center, as it works in unison with the pituitary, liken to the captain of a ship or so-called "master gland," and the pineal glands which act as second-in-command.7 Hormonal regulation in the body is a complicated feedback. The hypothalamus controls the ten various hormones released by the pituitary. The hypothalamus secretes releasing factors; these factors control the hormones released by the pituitary gland. Like a domino effect, the pituitary hormones then stimulate the secretion of hormones from the thyroid, adrenals, and gonads (testes or ovaries). The hypothalamus acts as a thermostat. Whenever hormones rise or lower in the bloodstream, a signal is sent to the hypothalamus. It then takes the necessary corrections, which in turn cause the pituitary to either increase or decrease the hormones made by the thyroid, adrenals, and gonads. The pituitary gland cells, called somatotrophes, make growth hormones (GH), which are also called somatotrophin. Over 50 percent of cells manufactured by the pituitary gland are somatotrophes (GH). These growth hormones stay in one’s bloodstream long enough to stimulate its uptake into the liver, where it is converted into growth factors. The insulin like growth factor 1 (IGF-1) is the most important of these growth factors. IGF-1 is also known as somatomedin C, or growth hormone. IGF-1 is the hormone that stimulates the pancreas into producing insulin.8American Diabetes Association’s (ADA) definition for normal blood glucose levels is to be below 100 milligrams. The ADA states, "A person with glucose level above 100 milligrams should be considered ‘per-diabetic’ and should see a doctor." Who is most likely to get Type II Diabetes Mellitus, or as modern medicine has labeled "SYNDROME X"? Did you know there are over 18 million Americans walking around with Type II Diabetes, or "Syndrome X"? According to the ADA, of the 18 million people who have Type II Diabetes, over 7 million are walking around with this condition and don’t even know it. Also noted, there are over 41 million Americans with pre-diabetic conditions who will become full-blown Type II Diabetic if not treated in time. There are several factors that enter into why an individual will develop Type II Diabetes. Some of these factors one can control, while others can not be controlled. ACCORDING TO THE AMERICAN DIABETES ASSOCIATION (ADA), THE FOLLOWING ARE SOME CONTROLLABLE AS WELL AS UNCONTROLLABLE FACTORS REGARDING DIABETES:
Controllable factors are: A. Obesity and lack of physical activity. Obesity is the fastest growing concern in our country, along with lack of physical activity. These two factors are the cause of the frightening rise of Type II Diabetes in our population. Obesity is a global affliction, according to the International Obesity Task Force. Their studies indicate that there are over 1.7 billion people on our planet who need to lose weight. One could postulate that along with a sedentary lifestyle, the fast food "super-sizer" is one of the main culprits in obesity. Ninety-nine percent of the time, one may choose their own destiny by either: (1) limiting the number of "super-sizers" and some exercise or (2) eat as many of the "super-sizers" as one wants, and limited or no exertion – then, in turn, sue the fast food restaurant for making one obese. B. High blood pressure and/or high cholesterol. Either one or both of these two conditions will make one more prone to Type II Diabetes. In nine out of ten cases where these two conditions exist, the individuals are most likely overweight. It has been stated that about 80 percent of people with Type II Diabetes are overweight, and have both high blood pressure and high cholesterol levels in their blood.9 The glycemic index is a measure used after a meal to observe how fast carbohydrates enter one’s bloodstream and thus raise one’s blood sugar level. Food, which is higher on the glycemic index, secretes more insulin. The fat metabolism process of the growth hormone is blocked, just as the growth hormone interferes with the fat-storage action of insulin, thus causing a "round robin" effect. Please note, on the glycemic index, the high numbers associated with pastas and grains. Not only do these cause weight gain, but they also cause a rate increase in insulin resistant, Type II Diabetes. It is generally accepted amongst dietitians and other health professionals that fiber-rich food is often the same food that is low glycemic food, and seems to have less effect on one’s blood sugar level. To manage one’s diabetes, a diabetic person should try to use the glycemic food pyramid chart concerning food purchases. Uncontrollable risk factors: A. Family History. Family history of diabetes plays a very important role in an individual developing this disease. B. Age. Type II Diabetes is more prevalent in people over age 40, especially if they are inactive. Type II Diabetes is rising at a frightening rate among young people today, due mostly to a poor diet (too many "super-sizers"), and lack of activity. C. Ethnic groups. Blacks, Mexicans, Native Indians, and Asians are more likely to develop diabetes than their Caucasian counterparts. The more risk factors in one’s background, the more likely one will develop Type II Diabetes. One may take control of one’s life with (1) proper exercise and (2) healthy eating habits. If one would concentrate on these two factors, along with the daily ingestion of two tablespoons of InsulClear™ (patent pending), one may minimize the risk of Type II Diabetes. I believe it is widely agreed and accepted throughout the world that conscientious control of one’s blood sugar levels will reduce one’s risk of becoming a Type II Diabetic and even delay the onset of further complications, such as: A. Heart disease, which is the #1 killer of all Americans. Heart disease does not and can not distinguish one’s sex or race. Women have the dubious distinction of catching up to men in deaths. In fact, more women die from their first heart attack than men do. A recent study published in Diabetes Care states, "Women with diabetes were more than nine times as likely to have heart attacks as other women who did not have diabetes and more likely to die from them." A sign to watch for concerning a pending heart attack with diabetics is a nagging feeling of nausea. Diabetics do not have the usual signs of a typical heart attack victim. When diabetics have a nagging nauseous feeling, this could be a warning of a pending heart attack and they should contact their doctor immediately.
B. Eye disorders, such as cataracts, glaucoma, and retinopathy may lead to blindness. These disorders are most common in people with diabetes. C. Kidney damage is another problem for people with diabetes. Approximately 10 percent of all Type II Diabetics will develop kidney failure and will need dialysis with a kidney transplant imminent. D. Nerve damage in a Type II Diabetic often appears as numbness in one’s extremities, such as the feet or hands. One may also suffer sexual problems, digestive distress, and low blood pressure. Open sores in one’s feet may not be felt and worsen with infection, gangrene, and possible amputation due to nerve damage. E. Skin conditions are due to high blood sugar levels, which can lead to skin rashes, discoloration, and dry flaky epidermis. F. Gum disease is a target of diabetes, because infections are harder to combat. Thus, one’s mouth becomes a breeding ground for germs. G. Infections are a part of diabetes. It is most difficult for one’s body to fight against bladder, kidney, vagina, gum, feet, and skin diseases. In other words, one’s entire body is affected in one way or another. A BIG NOTE: Gestational diabetes is a third type of diabetes. This is a temporary condition, occurring in women who are pregnant. This is a condition that goes unnoticed in most cases, because of the mild characteristic symptoms of excessive hunger, thirst, and frequent urination. Most women believe this is part of being pregnant. It is not!!!!! I stress, it is not!!!!! The elevated blood sugar levels in ones blood could be damaging to the fetus. However, in most cases it can be controlled with exercise, a proper diet, and B-6. Women who develop Type II Diabetes before the baby is born or have a large baby of nine pounds or heavier have a greater chance of developing diabetes later in life.10 It is very important to know Type II Diabetes does not control your life: You control your own destiny concerning Type II Diabetes. Exercise and healthy eating habits, along with ingesting 18 to 23 grams of InsulClear™ will be an excellent start toward a healthier lifestyle.
What are some of the first symptoms of the onset of diabetes, which may develop gradually over a given time period?
Other symptoms may also include:
"Our studies have shown systemic administration of the composition InsulClear™ will have a dramatic effect on people suffering from Type II Diabetes. Our studies have also shown people being able to reduce their insulin and/or pills, and in many instances have been able to stop taking these drugs completely." _____________________________________________________________ Vitamin E: Chemical name tocopherol. There are eight vitamin E isomers in nature. Research indicates only d-alpha tocopherol is biologically active. Vitamin E in the synthetic form is dl, it is not absorbed as well as the natural form of vitamin E.11 Alpha tocopherol is unstable; therefore it is stabilized by adding acetic acid to produce alpha tocopherol acetate, which converts into alpha tocopherol within the body. Tocopherol, or vitamin E, has been found to help reduce insulin levels in diabetics.12 It is a very powerful antioxidant that helps one’s body to protect itself against free radicals. Vitamins E and C (vitamin C will be elaborated on later) are like carp fish, which are scavengers of waterways. Similarly, vitamins E and C synergistically clean up free radicals within one’s body before they are able to perpetuate damage on the cellular structure. They function jointly to help keep blood vessels healthy.13 Free radicals emit very high levels of energy in their process of bonding or uniting with other free radicals, thereby causing damage to sensitive cell membranes that protect the cells. They can possibly infiltrate the cell nucleus, causing damage to the DNA within the nuclei. Damaged DNA will play havoc with one’s body by producing all sorts of mutants, which will trigger irregular cell growth, and in turn cause many diseases, some of which are heart disease, vascular disease, diabetes, cancer, Parkinson’s disease, arthritis, and premature aging, to name just a few. Vitamin E has been shown to help in keeping the blood plates less sticky, thus avoiding a blood clot, heart attack, or stroke. It also stops the oxidation process (rusting) in one’s body.14 Vitamin C: Chemically called ascorbic acid or ester C polyascorbate. The human body is unable to manufacture vitamin C, and it must be obtained from an outside source. Like vitamin E, vitamin C is a very powerful antioxidant. They work synergistically, with vitamin E being the scavenger of free oxygen radicals in the cell membrane, while vitamin C breaks the free radical chain in biologic fluids. Vitamin C is an energy supply for metabolism of each cell and supplies the bioenergy carrier molecules of the vitamin B group with lifesaving bioenergy. It affects one’s body the same as vitamin E. In addition, it helps with healing wounds, prevents fatigue, lowers blood serum cholesterol, heals bleeding gums, strengthens all connective tissues, promotes capillary integrity, and helps to decrease the severity of the common cold. Vitamin C is also responsible for the optimum production and function for collagen, elastin, healing lesions inside blood vessel walls, protection of the cardiovascular system, and production of antistress hormones. These are just a few of the natural healing properties of vitamin C. Vitamin C is needed for the metabolism of folic acid, tyrosine, and phenylalanine. It is also needed for interferon production, and it helps stop the oxidation process (rusting) in one’s body.15 Vitamin C reduces the lipid production in ones brain and spinal cord, where free radical damage frequently occurs. It is also needed to cross over the blood-brain barrier .16
DHEA: Dehydroepiandrosterone. What is DHEA? A super hormone! In one’s pituitary axis is where the production of DHEA begins, which in turn releases adrenocorticotrophic hormone (ACTH). ACTH signals the adrenal glands, located on top of one’s kidneys, as well as signaling one’s brain and one’s skin to manufacture dehydroepiandrosterone (DHEA) and its sulfate ester, dehydroepiandrosterone sulfate (DHEAS) from cholesterol (a lipid). DHEA is produced in other parts of one’s body such as the testicles and ovaries. Cholesterol in one’s body is the starting material used in all steroid hormones produced in the body. Pregnenolone is on the very top of the hormone pyramid, converted from cholesterol. It is then converted into DHEA as well as other sex hormones including (male) testosterone, (female) estrogen, and progesterone. It is the most abundant steroid released into the bloodstream. DHEA is dubbed "the mother of all steroids," as it is the most abundant steroid in one’s human body and is involved in the manufacture of testosterone, estrogen, progesterone, and corticosterone. The adrenal gland is responsible for secreting several hormones, one of which is DHEA and DHEAS. DHEA helps to increase insulin sensitivity in one’s body and enhances one’s immune system, as well as aids in the proliferation of T-cell growth by the thymus gland, which is a primary organ of the immune system. 17 DHEA seems to help prevent excess amounts of oxidized fat in the bloodstream by inhibiting glucose-6-phosphate dehydrogenase (G6PDH), an enzyme that breaks down glucose into fat. This fat, when released into the bloodstream, will cause inflammation and injury to the cell and the artery walls. Catabolic, an energy-yielding pathway, and anabolic, a biosynthetic pathway, are two glucose–metabolizing pathways in one’s body. It so happens that G6PDH is the first enzyme in the biosynthetic pathway; it is the one that synthesizes fatty acids and ribose (the sugar used in making deoxyribonucleic acid or DNA). The ability of DHEA to inhibit G6PDH may, in fact, redirect glucose from anabolic fat production into catabolic energy metabolism, thus creating a leaner metabolism.18 It also helps blood platelets from sticking together, thus life threatening blood clotting within one’s vascular network is kept from forming. Notably, DHEA is an antioxidant working synergistically with vitamins C and E within one’s body to prevent free radical damage to the DNA inside the cell. Speculation is that DHEA may stimulate the liver to produce more IGF-1 and growth hormone, which in turn stimulates the pituitary gland to generate more HGH (human growth hormones), which in turn affects the insulin output in Type II Diabetics.L-Glutamine: This is the most abundant amino acid in one’s body. It is a conditional essential amino acid, which means when one’s body is under a stressful situation, such as a life or death situation in one’s family life, one’s body may not be able to synthesize all it needs and will need an outside source. It acts as a releaser of the GH hormone, which in turn affects the IGF-1. Glutamine is a key element in the metabolism and maintenance of the immune system. It is essential for DNA synthesis, cell growth, and division, along with all factors that are enhanced by the release of GH, as well as one’s energy and alertness. 19 Glutamine acts as a neurotransmitter by forming the amino acid derivative γ-Amino butyrate, called gamma-amino butyric or GABA. GABA is formed by decarboxylase of glutamate. It is converted to glutamic acid in the brain, which is essential for cerebral function and increases the amount of GABA in one’s body.20L-Arginine: This is an essential amino acid that plays an important role in one’s body. Sometimes it is referred to as "the natural viagra." It helps to increase the blood flow to one’s penis and helps in the increase of sperm count. 21 L-Arginine is a necessary amino acid for normal function of one’s pituitary gland in the release of growth hormones (GH). It is most famous for its ability to stimulate the release of GH.22 Arginine can split off a molecule called nitric oxide. This molecule has a very important part in helping to relax one’s blood vessel walls, thereby normalizing high blood pressure. Nitric oxide also acts as an anti-clogging agent by decreasing the stickiness of blood platelets, allowing them to flow freely through one’s immense vascular system. It helps with the metabolizing of stored body fat.23 This essential amino acid is needed for protein synthesis, and it aids in liver detoxification and cirrhosis of the liver. It also aids in the release of growth hormones, increases one’s muscle mass, aids in kidney disorders, and helps in maintaining a healthy immune system. NOTE: Pregnant or lactating women should not consume L-Arginine.24L-Ornithine: It is a nonessential amino acid that does not occur in proteins within one’s body. Note nonessential does not mean unimportant. Its primary role in one’s body is urea cycle, which makes it very important in the removal of ammonia, especially in athletes. It helps to increase the potency of arginine, and is sometimes referred to as "son arginine." 25 The dynamic amino duo - when combined with arginine, it enhances the production and release of growth hormone (GH) as well as insulin in one’s body. Ornithine stimulates insulin secretion in one’s body and helps insulin work as an anabolic (muscle-building) hormone.26 When combined with L-arginine and L-carnitine, the growth hormone it helps to release, it aids one’s body in the metabolism of excess body fat. This amino acid is necessary for the immune system and liver function. It also helps in detoxifying ammonia and promotes wound healing.27L-Lysine: It is an essential amino acid that helps in repair and building of new body tissue (collagen), bone formation, and a stability factor in one’s artery walls. It also helps in the reversal of plaque build-up. It is vital in producing antibodies, hormones, enzymes, and body cells, and even helps in one’s concentration. 28 Like ornithine, lysine is an arginine booster and is essential for growth of bones, height, and genital function.29 Lysine has shown to help boost carnitine levels in one’s body because it is the parent molecule from which carnitine is made; however, to accomplish this conversion from lysine into carnitine requires the presence of vitamin C to act as a biocatalyst. The combined use of the amino acids lysine and arginine results in the release of biological active hormones able to affect peripheral cellular receptors, and thus cell growth in general.30R(+)-Alpha Lipoic Acid (ALA): It is a very powerful, natural antioxidant that is able to regenerate itself, and helps to regenerate intercellular glutathione, which is present in all of our cells and is responsible for expunging all types of free radicals and toxins from one’s body. ALA not only has the unique ability to regenerate itself in the fight against free radicals, as stated above, but can also regenerate other antioxidants, such as vitamins C and E. Glutathione supplements do not seem to have any effect on one’s body, as they seem to pass through one’s gut and are eliminated as waste. However, ALA can stimulate one’s body into producing this very important antioxidant during times of excessive stress or toxic substances. ALA is the only know antioxidant that is both fat and water-soluble. Being both fat and water-soluble allows it to enter all parts of one’s cellular structure, allowing it to trap those damaging, pesky free radicals. It has shown the ability to cross the blood/brain barrier and can increase the levels of glutathione in one’s brain, which destroys the free radials present. These free radicals are associated with brain disorders such as Parkinson’s disease, Alzheimer’s disease, dementia, and stroke. There have been several studies using R(+)-alpha lipoic acid as a treatment for Type II Diabetes. One such study conducted by the University of Heidelberg in Germany concluded that ALA played a major role in stopping the progression of diabetic kidney disease. It reduces oxidative stress and urinary protein excretion, helps those with diabetic neuropathy, and slows the progression of endothelial cell damage. ALA is essential for energy. It helps the cell mitochondria to break down the sugar along with oxygen for the production of adenosine triphosphate (ATP), the fuel that the mitochondria needs to run one’s body. 31Selenium: It is a trace mineral that helps to stimulate the immune system. Together, selenium, vitamin E, and vitamin C are synergistic antioxidants, which means they are stronger working together as one, rather than by themselves. Even though selenium is a trace mineral, it is also an antioxidant enzyme called glutathione peroxidase. Working together, they play an important role in cellular immunity within one’s body. Selenium also aids in keeping the elasticity in one’s body tissue and helps with repair of the DNA. It stops the oxidation process (rusting) in one’s body. It works with iodine in one’s body for proper function of one’s thyroid. 32Chromium Polynicotinate: It is one of the essential 14 trace minerals needed in one’s body. It helps one’s body to utilize protein and works with insulin in the metabolism of sugar, especially glucose intolerance. The three most popular forms are high chromium brewer’s-type yeast, chromium picolinate, and chromium polynicotinate. All three forms are well utilized and there is little or no evidence that one is better than the other. 33 When used with L-carnitine tartrate, it has shown to help with weight loss (being overweight is one of the contributory factors in Type II Diabetes). Chromium binds insulin to the receptor sites on the cell membrane. Insulin is affected by growth hormone (GH), which is produced by the anterior pituitary gland and controlled by the hypothalamus as to the amount of secreted hormone (GH). The liver then breaks down the GH, releasing insulin-like growth factor-1 (IGF-1). Another name for IGF-1 is so/mat/o/med/inc, which determines insulin hormone levels manufactured by the pancreas. GH and IGF-1 can go further than the antioxidant supplements vitamins C and E by acting like carriers bringing to the cell raw materials needed for rejuvenation and repair. Nucleic acids, which are delivered directly into the cell nucleus by the IGF-1, are used to repair damaged DNA and stimulate cell growth. GH and IGF-1 are in direct proportion with one another. When one of the two increases, the other increases. Likewise, if one decreases the other does also. It is a premise that in nucleic acid metabolism, chromium is involved in maintaining the structural integrity of one’s nuclear strands and regulation of gene expression within the confines of the body. Chromium is directly involved in nucleic acid metabolism, as well as carbohydrate and lipid metabolism.34 According to Michael Eades, M.D., "The insulin receptor, the structure on the surfaces of cells that actually become resistant to insulin, requires chromium to function properly." Whenever insulin or glucose enters one’s bloodstream, chromium is released to combat and normalize insulin levels. According to Dr. Philpott, "Even the slightest deficiency of chromium upsets the body’s tolerance to glucose."35Magnesium: This essential trace mineral is vital to optimizing cellular metabolism of minerals and promotes tissue growth, which includes bone growth. Magnesium also lowers one’s blood pressure and helps to stabilize tension of one’s vascular system. It is quite essential to maintain a healthy brain. To make energy, those tiny elongated rod-shaped structures within one’s cells, called the mitochondria, need to have magnesium. Essential for calcium and vitamin C metabolism, it is also essential for normal functioning of one’s cardiovascular, and aids in maintaining proper pH balance. Furthermore, magnesium is very important for the transmission of nerve and muscle impulses within the muscular and nervous system. In some circles, it is classified as the "antistress mineral." Magnesium is being used as damage control in many hospital emergency rooms to prevent further damage to the heart in heart attack victims. As one can see, magnesium plays many metabolic and structural roles. 36Manganese: It is a trace mineral that acts as an enzyme activator, along with helping the proper utilization of vitamin E and other minerals. Manganese is needed for proper protein and fat metabolism, as well as for a healthy immune system and blood sugar regulation.37 Manganese is a must for energy production. It is a component of enzymes and a powerful antioxidant called superoxide dismutase (SOD). It is essential for formation of bone and connective tissue, helps collagen synthesis, and facilities carbohydrate metabolism.38 SOD and its partner, catalase (an enzyme that decomposes hydrogen peroxide into water and oxygen), revitalizes the cells and reduces the rate of cell destruction. As a powerful antioxidant, SOD removes the most common damaging free radicals from one’s cells. This antioxidant also aids in the body’s utilization of zinc, copper, and manganese. 39Zinc Picolinate: It is a trace mineral that helps normal tissue function and protein and carbohydrate metabolism. Zinc is an essential catalyst for most integral body functions and related is to the B-vitamin niacin. It is also a constituent of insulin, which is necessary for metabolism. Zinc is essential for the synthesis of protein and enzyme action within one’s body. It is also a blood stabilizer and maintains the relationship between acid and alkaline in one’s blood and other body fluids. Zinc is a crucial nutrient for the immune system to function. Zinc picolinate is absorbed better than inorganic zinc salts such as zinc oxide or sulfate. 40Acetyl-L-Carnitine: Acetyl-L-carnitine, along with L-carnitine, are together extremely helpful in the protecting of one’s mental capacity as well as one’s body from the harmful effects of stress. They help to balance out the fats in one’s blood and within the cells; they are also a major factor in the fight against free radicals that damage or destroy one’s cells. Acetyl-L-carnitine increases levels of nerve growth factor (NGF), an important brain-healing compound. NGF plays a very important role in preserving neurons, especially those that make up the valuable brain messenger molecule called "acetylcholine," a chemical neurotransmitter. 41 Acetyl-L-carnitine helps to maintain the "myelin sheath" around one’s nerves. This is very important because without myelin, our nerves can not transmit and function at optimal speed. Acetyl-L-carnitine helps to protect the genetic integrity within the mitochondria (DNA-RNA).L-Carnitine Tartate: This antioxidant is one of the best sources of fat burners one can use. Pure L-carnitine tartrate works best; other forms of this powerful antioxidant are not as pure and do not work as well. It not only plays a critical role in fat burning, it also greatly enhances energy and endurance in athletes. L-carnitine helps to energize the cells of one’s immune system, thus promoting better immune protection for one’s body. Studies have shown that L-carnitine plays many roles in preventing complications of diabetes. As stated above, it is a primary fat burning nutrient that plays an important role in optimal carbohydrate metabolism within one’s body. It helps to keep insulin levels low, as well as helps one’s body to utilize insulin in the most effective way. L-carnitine promotes optimal blood sugar levels in diabetics. Hypoglycemia can be controlled very easily with the intake of L-carnitine each morning. Low blood sugar can lead to myriad problems, such as depression, high and low swing of energy levels, fatigue, poor brain function, and carbohydrate cravings, to name a few. It improves the supply of bioenergy for the mitochondria (the body’s power plants) of the millions of cells in one’s body. Hypothyroidism is another problem for Type II Diabetics. Hypothyroid patients have elevated levels of fats in their blood when the thyroid hormone output is low. L-carnitine is able to correct this by increasing energy, stimulating weight loss, lowering triglycerides, and increasing one’s mental stamina. These, and many other reasons, are why L-carnitine is essential for the Type II Diabetic. 42B6-Pyridoxine: This water-soluble vitamin is one of the most important vitamins needed in the metabolism of all the chemicals necessary for one’s nerve cell (neuron) communication. Researchers have discovered that pyridoxine is involved in more functions within one’s body than any other single nutrient. It is a necessary element for the production of hydrochloric acid and the absorption of fats and protein. 43 It has shown to help one in decreasing the need for insulin, along with aiding in the conversion of tryptophan to niacin, helping to assimilate protein and fat within one’s body and working as a natural diuretic. It is needed in the production of red blood cells and the carrier of oxygen to the cells within one’s cardiovascular system, as well as a co-factor for the metabolism of amino acids and proteins. It is essential for the optimum structure and function of collagen fibers. It is also a precursor of the enzyme phosphorylase, which is important in breaking down glycogen. Pyridoxine is required for one’s nervous system, as well as for one’s normal brain and the synthesis for RNA and DNA.B2-Riboflavin: This water-soluble vitamin nutrient helps one’s body to generate antibodies to fight off various diseases, and is beneficial in the metabolism of fats, carbohydrates, and proteins. It is essential in optimizing cellular metabolism and the delivery of bioenergy to the cells within one’s body. It is a structural component of two coenzymes of the energy transport molecule "flavin-adenine-dinucleotide" (FAD) and flavin mononucleotide (FMN). This is one of the most important carrier molecules of cellular energy inside the mitochondria in all cells. It is an important electron transporter of glutamates, amino acids, and beta-oxidation of fatty acids. It is a vital nutrient for healthy body tissues, particularly one’s skin, eyes, and nerves. 44 Riboflavin is necessary for one to manufacture red blood cells, antibody production, cell respiration, and cell growth.45Biotin-B-Vitamin Component: It is a water-soluble and a mobile carrier of activated CO 2. The carboxyl terminus of biotin is linked to the є- amino group of a specified lysine residue by an amide bond. Biotin is attached to pyruvate carboxylase by a long, flexible chain like that of lipoamide in the pyruvate dehydrogenase complex. This long flexible link between biotin and its carrier protein enables the activated carboxyl group to move from one active site to another within the enzyme-grouping complex. It is a mitochondrial enzyme and works synergistically with insulin, helping to metabolize and the efficient utilization within one’s body.46 Biotin aids in new cell growth, fatty acid production, in the metabolism of carbohydrates, fats, and proteins, and helps in the utilization of B-vitamins. It is also very important for healthy hair, skin, nerve tissue, bone marrow, andsweat glands. 47Folic Acid -B-Vitamin Component: It is an essential water-soluble, vitamin B nutrient that is needed for the formation of red blood cells by its action within one’s bone marrow. It also aids in protein metabolism and contributes to normal body growth. It acts as bioenergy molecules, transporter of oxygen to all the cells within one’s body. 48 Folic acid is essential for cell division in one’s body and is important for the production of nucleic acids (RNA and DNA). It is also needed for utilizing sugar and amino acids, and to ward off nutritional macrocytic anemia.49B12: Also known as cobalamin, it is a group of cobalt-containing compounds that display vitamin B12 activity. B12 is an energy vitamin and helps the body in new cell growth, nerve-tissue development, and folate metabolism, along with DNA synthesis. It is water-soluble and aids in the breakdown of amino acid homocysteine, lowering the risk of a heart attack. It also helps with the proper utilization of fats, carbohydrates, and protein. 50 B12 is not absorbed well through the stomach; therefore it is recommend to use the sublingual form accompanied by sorbitol (C6H14O6), used in manufacturing ascorbic acid and a moistening agent. This allows B12 to be better absorbed in the small intestine.51Soy Phospholipids: This excellent source of nutrient contains phosphatidylserine, phosphatidylinositol, phosphatidylethanolamine and phosphatidylglycerol. All living things that walk, talk, fly, or crawl, and plants, as well as bacterium, must have a certain amount of phospholipids for cell growth. Phospholipids have both hydrophilic and hydrophobic properties to the molecule and possible function as an emulsifying agent to maintain the proper colloidal state of protoplasm. It is thought that somehow they are considered to play a role in the transport of hydrophobic constituents into and out of cells within one’s body. An important role of phospholipids and their metabolites is the intercellular signaling. 52Soy Protein: Soy protein has an excellent serum cholesterol lowering effect on one’s body. It is a plant legume protein, rich in soluble and insoluble fiber, along with an abundance of isoflavones. Protein is the master builder of one’s body. This one basic nutrient is capable of repairing, building, and maintaining all the tissues within the human body. Protein is the building block for muscle growth; growth hormone uses this protein in building a lean, sculptured body. For this reason, many bodybuilders will consume high soy protein drinks. 53Soy protein nutrients reduce the negative effects of hyperglycemia on one’s LDL cholesterol. Hyperglycemia can cause nerve damage as well as LDL cholesterol, being changed into even worse LDL cholesterol plaque, which plugs one’s arteries. Soy protein has shown to reverse these effects. Chronic renal failure is one of the symptoms of Type II Diabetes. Soy protein helps to maintain a healthy kidney by improving the kidney filtration function, filtering out all impurities. 54Milk Thistle Ext (80% silymarin): Milk thistle is a herb and has been used in Europe for over a millennia as a liver tonic. It has been used to treat a plethora of chronic liver and gall bladder conditions, including hepatitis and cirrhosis. Exciting clinical data is highlighting the reversal of toxic liver damage from alcoholism, drug-induced, fatty degeneration of the liver. In a recent article in a European journal, it is stated that milk thistle "is undoubtedly the best documented pharmaceutical agent for the treatment for liver diseases." 55 It is an active flavonoid silymarin, which has antioxidant ability. It can be used for all liver disorders, such as jaundice and hepatitis. Milk thistle contains some of the most potent liver-protection substances known to man. It acts as an antioxidant preventing free radical damage to the liver, as well as stimulating new liver cell growth, and also protects one’s kidneys from free radical damage.56 Glutathione plays a critical role in the liver being able to detoxify various toxins successfully. Many toxins tend to reduce the glutathione in one’s liver, thus making the liver more susceptible to damage. Milk thistle (silymarin) prevents the liver from depleting glutathione levels, and in many cases has increased the level of glutathione.Gymnema Sylvestre: This herb has been used in India for approximately 2,000 years in treatment of diabetes. In the Hindi dialect language of northern India, it is called "gumar," or "sugar destroyer." This herb is a woody climbing vine that grows in central and southern India. According to research studies, the leaves of this woody vine are used to raise insulin levels in one’s body by regenerating cells in one’s pancreas, which in turn secretes necessary increase in insulin. 57 It was first documented in the late 1920s the effect of gymnema leaves on lowering blood sugar (hypoglycemic) in a diabetic.58 The term "sugar destroyer" can be taken literally. When placed on one’s tongue or when the leaves are chewed, one will lose all ability to taste sweets.59 There also has been evidence that gymnema leaves have an effect on lowering serum triglycerides and the bad cholesterol (LDL) in heart disease.
In conclusion, know your cardiovascular risk factor numbers and manage your ABCs. According to the American Diabetes Association, one should try to adhere to the following target levels in their ABCs. These numbers may vary somewhat from people who have diabetes to ones who do not; however, they are a good gage to start with: A. A-one-C (A-1-C) measures average blood sugar levels over 2-3 months should be below 7. B. Blood pressure should be below 130/80; American Heart Association says 118/79 or below. C. Cholesterol bad cholesterol low density lipoprotein (LDL) should be below 100mg/dl. High Density Lipoprotein (HDL) should be above 50mg/dl for women and 40mg/dl for men. Triglycerides for both men and women should be below 150mg/dl. All of the enclosed information has been gleaned from various websites, along with the referenced material listed below. For more information regarding diabetes, please visit these websites: www.aadenet.org www.diabetes.org www.eatright.org www.diabetes.ca/ www.niddk.nih.gov/ www.cdc.gov/nccdphp/ddt/dthome.htm www.cdc.gov/diabetes/pubs/factsheet.htm www.diabeticgourmet.com www.cancernews.com/diabetes www.diabetesstation.org
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Pashko; The Biological Significance of dehydroepiandrosterone. In: The biologic Role of Dehydroepiandrosterone (DHEA), Mohammed Kalimi and William Regelson [Eds], Walter de Gruyter, New York 1990. 19. Dr. Ronald Klatz. Grow Young with HGH: 1998; 206 /207 20. James F. Balch, M.D., Phyllis A. Balch, C.N.C.: Prescription for Nutritional Healing. Pg.29 21. Earl Mindells’sR.P.H.,Ph.D: Vitamin Bible for the 21st. Century;1999:125 22. Daniel Gastelu.Dr. Fred Hatfiled: Dynamic Nutrition for Maximum Performance:1997;37 23. Matthias Rath, M.D., The Heart, Cellular Health Series: 2001: 160 24. James F. Balch, M.D., Phyllis A. Balch, C.N.C. Prescription for Nutritional Healing: 1990: 28 25. Daniel Gastelu.Dr. Fred Hatfiled: Dynamic Nutrition for Maximum Performance:1997;7;41-42 26. Earl Mindells’sR.P.H.,Ph.D: Vitamin Bible for the 21st. Century;1999:128-129 27. James F. Balch, M.D., Phyllis A. Balch, C.N.C. Prescription for Nutritional Healing: 1990: 30 28. 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